Genetics and Neurobiology of Down Syndrome

Bani Ganguly
Elsevier
498 pages
ISBN: 9780323904568
September 2022

This book provides a thorough review of the genetic etiology and mechanisms of trisomy 21. It discusses the history of the syndrome, along with the clinical features and health consequences, including physical features, cognitive, and neurologic symptoms. Genetic counseling on pros and cons of prenatal screening and testing and associated ethical issues are explored. It also covers the societal and demographic aspects as well as the future direction of therapeutic development.