Molecular, Cellular, and Metabolic Fundamentals of Human Aging

Evandro Fei Fang, Linda Hildegard Bergersen, Brian Gilmour
Elsevier
260 pages
ISBN: 9780323916172
October 2022

This book provides an overview of the main aging mechanisms and physiology and how they can lead to age-related diseases and conditions. Topics include DNA damage and how ineffective repair can lead to cell and tissue aging and decreased functionality, loss of proteostasis, changes to feeding and fasting pathways, mitochondrial dysfunction, the impact of decreased ability of autophagosomes and autophagosomes, cellular senescence, changes to communication molecules, and the impact of stem cell exhaustion.